HuLG002410

Entrez Gene ID

3594

Official Gene Symbol

IL12RB1

Synonyms

CD212|ILN12RNBETA1|IL12RB|MGC34454

Gene name

interleukin 12 receptor, beta 1

Gene Type

protein-coding

Chromosome

19

Genomics Location

19p13.1

Known cancer genes

Yes

Protein products

Interleukin-12 receptor subunit beta-1

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Biliary cirrhosis

Database cross reference

HGNC:5971
MIM:601604
Ensembl:ENSG00000096996
HPRD:03363
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

GO annotation

GO:0001916

positive regulation of T cell mediated cytotoxicity

GO:0002230

positive regulation of defense response to virus by host

GO:0002827

positive regulation of T-helper 1 type immune response

GO:0004872

receptor activity

GO:0004896

cytokine receptor activity

GO:0005143

interleukin-12 receptor binding

GO:0007165

signal transduction

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016517

interleukin-12 receptor activity

GO:0019221

cytokine-mediated signaling pathway

GO:0032729

positive regulation of interferon-gamma production

GO:0035722

interleukin-12-mediated signaling pathway

GO:0042019

interleukin-23 binding

GO:0042020

interleukin-23 receptor activity

GO:0042022

interleukin-12 receptor complex

GO:0042104

positive regulation of activated T cell proliferation

GO:0043382

positive regulation of memory T cell differentiation

GO:0071346

cellular response to interferon-gamma

GO:0072536

interleukin-23 receptor complex

GO:2000318

positive regulation of T-helper 17 type immune response

GO:2000330

positive regulation of T-helper 17 cell lineage commitment