HuLG002453

Entrez Gene ID

3651

Official Gene Symbol

PDX1

Synonyms

GSF|IDXN1|IPF1|IUF1|MODY4|PDXN1|STFN1

Gene name

pancreatic and duodenal homeobox 1

Gene Type

protein-coding

Chromosome

13

Genomics Location

13q12.1

Known cancer genes

Yes

Protein products

Pancreas/duodenum homeobox protein 1

Database cross reference

HGNC:6107
MIM:600733
Ensembl:ENSG00000139515
HPRD:02843
RefSeq Genomic nucleotide accession:AC_000056
RefSeq Genomic nucleotide gi:89161191

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003309

type B pancreatic cell differentiation

GO:0003682

chromatin binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005634

nucleus

GO:0006006

glucose metabolic process

GO:0006091

generation of precursor metabolites and energy

GO:0006351

transcription, DNA-dependent

GO:0007263

nitric oxide mediated signal transduction

GO:0007275

multicellular organismal development

GO:0008284

positive regulation of cell proliferation

GO:0008285

negative regulation of cell proliferation

GO:0009887

organ morphogenesis

GO:0016331

morphogenesis of embryonic epithelium

GO:0030073

insulin secretion

GO:0031017

exocrine pancreas development

GO:0031018

endocrine pancreas development

GO:0042593

glucose homeostasis

GO:0043565

sequence-specific DNA binding

GO:0044424

intracellular part

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0051594

detection of glucose