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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002460

Entrez Gene ID

3659

Official Gene Symbol

IRF1

Synonyms

IRFN1|MAR

Gene name

interferon regulatory factor 1

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q31.1

Known cancer genes

Yes

Protein products

Interferon regulatory factor 1

IRF1 protein

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:6116
MIM:147575
Ensembl:ENSG00000125347
HPRD:00961
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006366

transcription from RNA polymerase II promoter

GO:0007596

blood coagulation

GO:0019221

cytokine-mediated signaling pathway

GO:0043374

CD8-positive, alpha-beta T cell differentiation

GO:0043565

sequence-specific DNA binding

GO:0045084

positive regulation of interleukin-12 biosynthetic process

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0060333

interferon-gamma-mediated signaling pathway

GO:0060337

type I interferon-mediated signaling pathway

GO:0071260

cellular response to mechanical stimulus