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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002461

Entrez Gene ID

3660

Official Gene Symbol

IRF2

Synonyms

DKFZp686F0244|IRFN2

Gene name

interferon regulatory factor 2

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q34.1-q35.1

Known cancer genes

Yes

Protein products

Interferon regulatory factor 2

IRF2 protein

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:6117
MIM:147576
Ensembl:ENSG00000168310
HPRD:00962
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005730

nucleolus

GO:0005925

focal adhesion

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0007596

blood coagulation

GO:0008283

cell proliferation

GO:0019221

cytokine-mediated signaling pathway

GO:0060333

interferon-gamma-mediated signaling pathway

GO:0060337

type I interferon-mediated signaling pathway