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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002466

Entrez Gene ID

3665

Official Gene Symbol

IRF7

Synonyms

IRFN7H|IRF7A

Gene name

interferon regulatory factor 7

Gene Type

protein-coding

Chromosome

11

Genomics Location

11p15.5

Protein products

Interferon regulatory factor 7

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Hepatocellular carcinoma

Database cross reference

HGNC:6122
MIM:605047
Ensembl:ENSG00000185507
HPRD:05441
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006355

regulation of transcription, DNA-dependent

GO:0008063

Toll signaling pathway

GO:0009615

response to virus

GO:0010008

endosome membrane

GO:0019221

cytokine-mediated signaling pathway

GO:0032727

positive regulation of interferon-alpha production

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0044419

interspecies interaction between organisms

GO:0045087

innate immune response

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0060333

interferon-gamma-mediated signaling pathway

GO:0060337

type I interferon-mediated signaling pathway