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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002472

Entrez Gene ID

3673

Official Gene Symbol

ITGA2

Synonyms

BR|CD49B|GPIa|VLAN2|VLAA2

Gene name

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q11.2

Known cancer genes

Yes

Protein products

Integrin alpha-2

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:6137
MIM:192974
Ensembl:ENSG00000164171
HPRD:01893
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004872

receptor activity

GO:0005515

protein binding

GO:0005518

collagen binding

GO:0005886

plasma membrane

GO:0007155

cell adhesion

GO:0007160

cell-matrix adhesion

GO:0007229

integrin-mediated signaling pathway

GO:0007411

axon guidance

GO:0007596

blood coagulation

GO:0008305

integrin complex

GO:0009887

organ morphogenesis

GO:0009897

external side of plasma membrane

GO:0009986

cell surface

GO:0016021

integral to membrane

GO:0042802

identical protein binding

GO:0044419

interspecies interaction between organisms