Gene basic information
| LiverAtlas Gene ID |
HuLG002485 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ITGB1 |
|
Synonyms |
CD29|FNRB|GPIIA|MDF2|MSK12|VLANBETA|VLAB |
|
Gene name |
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10p11.2 |
|
Known cancer genes |
Yes |
|
Protein products |
Integrin, beta 1 (Fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:6153
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0001669 |
acrosomal vesicle |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001708 |
cell fate specification |
|
GO:0001726 |
ruffle |
|
GO:0001894 |
tissue homeostasis |
|
GO:0001948 |
glycoprotein binding |
|
GO:0001968 |
fibronectin binding |
|
GO:0002020 |
protease binding |
|
GO:0002042 |
cell migration involved in sprouting angiogenesis |
|
GO:0003779 |
actin binding |
|
GO:0004872 |
receptor activity |
|
GO:0005178 |
integrin binding |
|
GO:0005515 |
protein binding |
|
GO:0005518 |
collagen binding |
|
GO:0005604 |
basement membrane |
|
GO:0005886 |
plasma membrane |
|
GO:0005911 |
cell-cell junction |
|
GO:0005912 |
adherens junction |
|
GO:0005925 |
focal adhesion |
|
GO:0006874 |
cellular calcium ion homeostasis |
|
GO:0006968 |
cellular defense response |
|
GO:0007155 |
cell adhesion |
|
GO:0007156 |
homophilic cell adhesion |
|
GO:0007159 |
leukocyte cell-cell adhesion |
|
GO:0007160 |
cell-matrix adhesion |
|
GO:0007229 |
integrin-mediated signaling pathway |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007411 |
axon guidance |
|
GO:0007596 |
blood coagulation |
|
GO:0008277 |
regulation of G-protein coupled receptor protein signaling pathway |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0008305 |
integrin complex |
|
GO:0008354 |
germ cell migration |
|
GO:0009986 |
cell surface |
|
GO:0010811 |
positive regulation of cell-substrate adhesion |
|
GO:0010976 |
positive regulation of neuron projection development |
|
GO:0014704 |
intercalated disc |
|
GO:0014823 |
response to activity |
|
GO:0016021 |
integral to membrane |
|
GO:0016477 |
cell migration |
|
GO:0019717 |
synaptosome |
|
GO:0019901 |
protein kinase binding |
|
GO:0019904 |
protein domain specific binding |
|
GO:0030056 |
hemidesmosome |
|
GO:0030183 |
B cell differentiation |
|
GO:0030335 |
positive regulation of cell migration |
|
GO:0031345 |
negative regulation of cell projection organization |
|
GO:0031594 |
neuromuscular junction |
|
GO:0031667 |
response to nutrient levels |
|
GO:0032154 |
cleavage furrow |
|
GO:0032587 |
ruffle membrane |
|
GO:0032594 |
protein transport within lipid bilayer |
|
GO:0033631 |
cell-cell adhesion mediated by integrin |
|
GO:0034329 |
cell junction assembly |
|
GO:0034667 |
alpha3-beta1 integrin complex |
|
GO:0034679 |
alpha9-beta1 integrin complex |
|
GO:0034698 |
response to gonadotropin stimulus |
|
GO:0042277 |
peptide binding |
|
GO:0042383 |
sarcolemma |
|
GO:0042470 |
melanosome |
|
GO:0042493 |
response to drug |
|
GO:0042802 |
identical protein binding |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043236 |
laminin binding |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045121 |
membrane raft |
|
GO:0045214 |
sarcomere organization |
|
GO:0045665 |
negative regulation of neuron differentiation |
|
GO:0045666 |
positive regulation of neuron differentiation |
|
GO:0045807 |
positive regulation of endocytosis |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0050776 |
regulation of immune response |
|
GO:0050900 |
leukocyte migration |
|
GO:0051393 |
alpha-actinin binding |
|
GO:0051726 |
regulation of cell cycle |
|
GO:0055007 |
cardiac muscle cell differentiation |
|
GO:0060135 |
maternal process involved in female pregnancy |
|
GO:0070830 |
tight junction assembly |
|
GO:0071260 |
cellular response to mechanical stimulus |
|
GO:0071305 |
cellular response to vitamin D |
|
GO:0071445 |
cellular response to protein stimulus |
|
GO:0071479 |
cellular response to ionizing radiation |
|
GO:0071559 |
response to transforming growth factor beta stimulus |
