Gene basic information
| LiverAtlas Gene ID |
HuLG002588 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
KIT |
|
Synonyms |
CNKit|CD117|PBT|SCFR |
|
Gene name |
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
|
Gene Type |
protein-coding |
|
Chromosome |
4 |
|
Genomics Location |
4q11-q12 |
|
Known cancer genes |
Yes |
|
Protein products |
Tyrosine-protein kinase receptor |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:6342
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001669 |
acrosomal vesicle |
|
GO:0002318 |
myeloid progenitor cell differentiation |
|
GO:0002320 |
lymphoid progenitor cell differentiation |
|
GO:0002573 |
myeloid leukocyte differentiation |
|
GO:0004713 |
protein tyrosine kinase activity |
|
GO:0004716 |
receptor signaling protein tyrosine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005020 |
stem cell factor receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005615 |
extracellular space |
|
GO:0005737 |
cytoplasm |
|
GO:0006687 |
glycosphingolipid metabolic process |
|
GO:0007165 |
signal transduction |
|
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
GO:0007243 |
intracellular protein kinase cascade |
|
GO:0007283 |
spermatogenesis |
|
GO:0007286 |
spermatid development |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008542 |
visual learning |
|
GO:0008584 |
male gonad development |
|
GO:0009314 |
response to radiation |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0009898 |
internal side of plasma membrane |
|
GO:0010628 |
positive regulation of gene expression |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0018108 |
peptidyl-tyrosine phosphorylation |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0030097 |
hemopoiesis |
|
GO:0030335 |
positive regulation of cell migration |
|
GO:0031274 |
positive regulation of pseudopodium assembly |
|
GO:0035019 |
somatic stem cell maintenance |
|
GO:0035234 |
germ cell programmed cell death |
|
GO:0043069 |
negative regulation of programmed cell death |
|
GO:0043406 |
positive regulation of MAP kinase activity |
|
GO:0045747 |
positive regulation of Notch signaling pathway |
|
GO:0046777 |
protein autophosphorylation |
|
GO:0048070 |
regulation of developmental pigmentation |
|
GO:0048103 |
somatic stem cell division |
|
GO:0048170 |
positive regulation of long-term neuronal synaptic plasticity |
|
GO:0050673 |
epithelial cell proliferation |
