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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002621

Entrez Gene ID

3856

Official Gene Symbol

KRT8

Synonyms

CARD2|CK8|CYK8|K2C8|K8|KO

Gene name

keratin 8

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q13

Known cancer genes

Yes

Protein products

Keratin, type II cytoskeletal 8

KRT8 protein

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Alcoholic hepatitis

Biliary cirrhosis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:6446
MIM:148060
Ensembl:ENSG00000170421
HPRD:01015
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005198

structural molecule activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005882

intermediate filament

GO:0007010

cytoskeleton organization

GO:0016363

nuclear matrix

GO:0044419

interspecies interaction between organisms

GO:0045095

keratin filament