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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002664

Entrez Gene ID

3929

Official Gene Symbol

LBP

Synonyms

MGC22233

Gene name

lipopolysaccharide binding protein

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q11.23

Known cancer genes

Yes

Protein products

Lipopolysaccharide-binding protein

LBP protein

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:6517
MIM:151990
Ensembl:ENSG00000129988
HPRD:07175
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001530

lipopolysaccharide binding

GO:0002232

leukocyte chemotaxis involved in inflammatory response

GO:0002281

macrophage activation involved in immune response

GO:0005102

receptor binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006810

transport

GO:0006869

lipid transport

GO:0006953

acute-phase response

GO:0006968

cellular defense response

GO:0008063

Toll signaling pathway

GO:0008228

opsonization

GO:0008289

lipid binding

GO:0015920

lipopolysaccharide transport

GO:0031663

lipopolysaccharide-mediated signaling pathway

GO:0032490

detection of molecule of bacterial origin

GO:0032496

response to lipopolysaccharide

GO:0032720

negative regulation of tumor necrosis factor production

GO:0032722

positive regulation of chemokine production

GO:0032755

positive regulation of interleukin-6 production

GO:0032757

positive regulation of interleukin-8 production

GO:0032760

positive regulation of tumor necrosis factor production

GO:0034145

positive regulation of toll-like receptor 4 signaling pathway

GO:0042535

positive regulation of tumor necrosis factor biosynthetic process

GO:0043032

positive regulation of macrophage activation

GO:0043498

cell surface binding

GO:0044130

negative regulation of growth of symbiont in host

GO:0045087

innate immune response

GO:0050829

defense response to Gram-negative bacterium

GO:0050830

defense response to Gram-positive bacterium

GO:0051636

Gram-negative bacterial cell surface binding

GO:0051637

Gram-positive bacterial cell surface binding

GO:0060265

positive regulation of respiratory burst involved in inflammatory response

GO:0070891

lipoteichoic acid binding

GO:0071222

cellular response to lipopolysaccharide

GO:0071223

cellular response to lipoteichoic acid

GO:0090023

positive regulation of neutrophil chemotaxis