Gene basic information
LiverAtlas Gene ID |
HuLG002666 |
Entrez Gene ID |
|
Official Gene Symbol |
LCAT |
Gene name |
lecithin-cholesterol acyltransferase |
Gene Type |
protein-coding |
Chromosome |
16 |
Genomics Location |
16q22.1 |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:6522
|
Liver relevance
Liver sepcificity |
Yes/No |
Yes |
Evidence |
Translational level from literatures |
|
Quality score |
|
|
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
GO:0004623 |
phospholipase A2 activity |
GO:0005515 |
protein binding |
GO:0005576 |
extracellular region |
GO:0005615 |
extracellular space |
GO:0006629 |
lipid metabolic process |
GO:0006644 |
phospholipid metabolic process |
GO:0006656 |
phosphatidylcholine biosynthetic process |
GO:0008202 |
steroid metabolic process |
GO:0008203 |
cholesterol metabolic process |
GO:0016740 |
transferase activity |
GO:0030301 |
cholesterol transport |
GO:0034186 |
apolipoprotein A-I binding |
GO:0034364 |
high-density lipoprotein particle |
GO:0034372 |
very-low-density lipoprotein particle remodeling |
GO:0034375 |
high-density lipoprotein particle remodeling |
GO:0034435 |
cholesterol esterification |
GO:0042157 |
lipoprotein metabolic process |
GO:0042158 |
lipoprotein biosynthetic process |
GO:0042632 |
cholesterol homeostasis |
GO:0043691 |
reverse cholesterol transport |
GO:0046688 |
response to copper ion |
GO:0051384 |
response to glucocorticoid stimulus |