Gene basic information
| LiverAtlas Gene ID |
HuLG002694 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
LIFR |
|
Synonyms |
CD118|FLJ98106|FLJ99923|LIFNR|SJS2|STWS|SWS |
|
Gene name |
leukemia inhibitory factor receptor alpha |
|
Gene Type |
protein-coding |
|
Chromosome |
5 |
|
Genomics Location |
5p13-p12 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ76704, highly similar to Homo sapiens leukemia inhibitory factor receptor (LIFR), mRNA |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:6597
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004872 |
receptor activity |
|
GO:0004897 |
ciliary neurotrophic factor receptor activity |
|
GO:0004923 |
leukemia inhibitory factor receptor activity |
|
GO:0004924 |
oncostatin-M receptor activity |
|
GO:0005127 |
ciliary neurotrophic factor receptor binding |
|
GO:0005576 |
extracellular region |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0019838 |
growth factor binding |
|
GO:0031100 |
organ regeneration |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0042221 |
response to chemical stimulus |
|
GO:0045768 |
positive regulation of anti-apoptosis |
|
GO:0048812 |
neuron projection morphogenesis |
|
GO:0048861 |
leukemia inhibitory factor signaling pathway |
|
GO:0070120 |
ciliary neurotrophic factor-mediated signaling pathway |
