Gene basic information
| LiverAtlas Gene ID |
HuLG002697 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
LIG4 |
|
Gene name |
ligase IV, DNA, ATP-dependent |
|
Gene Type |
protein-coding |
|
Chromosome |
13 |
|
Genomics Location |
13q33-q34 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Database cross reference |
HGNC:6601
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000012 |
single strand break repair |
|
GO:0000166 |
nucleotide binding |
|
GO:0000793 |
condensed chromosome |
|
GO:0001701 |
in utero embryonic development |
|
GO:0002328 |
pro-B cell differentiation |
|
GO:0003677 |
DNA binding |
|
GO:0003909 |
DNA ligase activity |
|
GO:0003910 |
DNA ligase (ATP) activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005622 |
intracellular |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0005925 |
focal adhesion |
|
GO:0005958 |
DNA-dependent protein kinase-DNA ligase 4 complex |
|
GO:0006260 |
DNA replication |
|
GO:0006266 |
DNA ligation |
|
GO:0006281 |
DNA repair |
|
GO:0006297 |
nucleotide-excision repair, DNA gap filling |
|
GO:0006302 |
double-strand break repair |
|
GO:0006303 |
double-strand break repair via nonhomologous end joining |
|
GO:0007049 |
cell cycle |
|
GO:0007417 |
central nervous system development |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0008283 |
cell proliferation |
|
GO:0010165 |
response to X-ray |
|
GO:0010332 |
response to gamma radiation |
|
GO:0016032 |
viral reproduction |
|
GO:0016874 |
ligase activity |
|
GO:0019047 |
provirus integration |
|
GO:0019059 |
initiation of viral infection |
|
GO:0032807 |
DNA ligase IV complex |
|
GO:0033077 |
T cell differentiation in thymus |
|
GO:0033151 |
V(D)J recombination |
|
GO:0033152 |
immunoglobulin V(D)J recombination |
|
GO:0033153 |
T cell receptor V(D)J recombination |
|
GO:0035019 |
somatic stem cell maintenance |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0045190 |
isotype switching |
|
GO:0046872 |
metal ion binding |
|
GO:0048146 |
positive regulation of fibroblast proliferation |
|
GO:0050769 |
positive regulation of neurogenesis |
|
GO:0051102 |
DNA ligation involved in DNA recombination |
|
GO:0051103 |
DNA ligation involved in DNA repair |
|
GO:0051276 |
chromosome organization |
|
GO:0051301 |
cell division |
|
GO:0051402 |
neuron apoptosis |
|
GO:0070419 |
nonhomologous end joining complex |
