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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002704

Entrez Gene ID

3990

Official Gene Symbol

LIPC

Synonyms

HDLCQ12|HL|HTGL|LIPH

Gene name

lipase, hepatic

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q21-q23

Known cancer genes

Yes

Protein products

LIPC protein

Hepatic triacylglycerol lipase

Related liver disease name

Hepatitis C

Chronic hepatitis C

Hepatocellular carcinoma

Database cross reference

HGNC:6619
MIM:151670
Ensembl:ENSG00000166035
HPRD:01058
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004620

phospholipase activity

GO:0004806

triglyceride lipase activity

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006633

fatty acid biosynthetic process

GO:0008201

heparin binding

GO:0008203

cholesterol metabolic process

GO:0016042

lipid catabolic process

GO:0016787

hydrolase activity

GO:0019433

triglyceride catabolic process

GO:0030169

low-density lipoprotein particle binding

GO:0034185

apolipoprotein binding

GO:0034364

high-density lipoprotein particle

GO:0034372

very-low-density lipoprotein particle remodeling

GO:0034373

intermediate-density lipoprotein particle remodeling

GO:0034374

low-density lipoprotein particle remodeling

GO:0034375

high-density lipoprotein particle remodeling

GO:0034382

chylomicron remnant clearance

GO:0034638

phosphatidylcholine catabolic process

GO:0042632

cholesterol homeostasis

GO:0043691

reverse cholesterol transport

GO:0070328

triglyceride homeostasis