HuLG002736

Entrez Gene ID

4041

Official Gene Symbol

LRP5

Synonyms

BMND1|EVR1|EVR4|HBM|LR3|LRP7|OPPG|OPS|OPTA1|VBCH2

Gene name

low density lipoprotein receptor-related protein 5

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13.4

Known cancer genes

Yes

Protein products

Low-density lipoprotein receptor-related protein 5

LDL receptor member LR3

Database cross reference

HGNC:6697
MIM:603506
Ensembl:ENSG00000162337
HPRD:04616
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

GO annotation

GO:0002053

positive regulation of mesenchymal cell proliferation

GO:0004872

receptor activity

GO:0005515

protein binding

GO:0005783

endoplasmic reticulum

GO:0005886

plasma membrane

GO:0006007

glucose catabolic process

GO:0006897

endocytosis

GO:0007166

cell surface receptor linked signaling pathway

GO:0007275

multicellular organismal development

GO:0008217

regulation of blood pressure

GO:0008284

positive regulation of cell proliferation

GO:0016021

integral to membrane

GO:0019534

toxin transporter activity

GO:0042632

cholesterol homeostasis

GO:0043235

receptor complex

GO:0044332

Wnt receptor signaling pathway involved in dorsal/ventral axis specification

GO:0045600

positive regulation of fat cell differentiation

GO:0045668

negative regulation of osteoblast differentiation

GO:0045840

positive regulation of mitosis

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048539

bone marrow development

GO:0060042

retina morphogenesis in camera-type eye

GO:0060070

canonical Wnt receptor signaling pathway

GO:0060349

bone morphogenesis

GO:0060612

adipose tissue development

GO:0060828

regulation of canonical Wnt receptor signaling pathway

GO:0061304

retinal blood vessel morphogenesis

GO:0071901

negative regulation of protein serine/threonine kinase activity