HuLG002745

Entrez Gene ID

4052

Official Gene Symbol

LTBP1

Synonyms

MGC163161

Gene name

latent transforming growth factor beta binding protein 1

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p22-p21

Known cancer genes

Yes

Protein products

LTBP1 protein

Uncharacterized protein

Latent-transforming growth factor beta-binding protein 1

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:6714
MIM:150390
Ensembl:ENSG00000049323
HPRD:01039
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

GO annotation

GO:0005024

transforming growth factor beta receptor activity

GO:0005488

binding

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0008150

biological process

GO:0019838

growth factor binding

GO:0031012

extracellular matrix

GO:0035583

negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta