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Gene basic information

LiverAtlas Gene ID

HuLG002747

Entrez Gene ID

4054

Official Gene Symbol

LTBP3

Synonyms

DKFZp586M2123|FLJ33431|FLJ39893|FLJ42533|FLJ44138|FLJ45576|LTBPN3|LTBP2|STHAG6|pp6425

Gene name

latent transforming growth factor beta binding protein 3

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13.1

Known cancer genes

Yes

Protein products

LTBP3 protein

Uncharacterized protein

Uncharacterized protein

Latent-transforming growth factor beta-binding protein 3

Putative uncharacterized protein pp6425

Related liver disease name

Liver fibrosis and liver cirrhosis

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:6716
MIM:602090
Ensembl:ENSG00000168056
HPRD:03649
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

 

Ontology annotation

GO ID

GO annotation

GO:0001501

skeletal system development

GO:0005488

binding

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0019838

growth factor binding

GO:0030502

negative regulation of bone mineralization

GO:0032331

negative regulation of chondrocyte differentiation

GO:0045780

positive regulation of bone resorption

GO:0046849

bone remodeling

GO:0060349

bone morphogenesis

GO:0060430

lung saccule development