Gene basic information
LiverAtlas Gene ID |
HuLG002777 |
Entrez Gene ID |
|
Official Gene Symbol |
SMAD5 |
Synonyms |
DKFZp781C1895|DKFZp781O1323|DWFC|JV5N1|MADH5 |
Gene name |
SMAD family member 5 |
Gene Type |
protein-coding |
Chromosome |
5 |
Genomics Location |
5q31 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:6771
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0005057 |
receptor signaling protein activity |
GO:0005515 |
protein binding |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0005654 |
nucleoplasm |
GO:0005667 |
transcription factor complex |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0006355 |
regulation of transcription, DNA-dependent |
GO:0007165 |
signal transduction |
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
GO:0009880 |
embryonic pattern specification |
GO:0016021 |
integral to membrane |
GO:0030509 |
BMP signaling pathway |
GO:0030618 |
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity |
GO:0031625 |
ubiquitin protein ligase binding |