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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002777

Entrez Gene ID

4090

Official Gene Symbol

SMAD5

Synonyms

DKFZp781C1895|DKFZp781O1323|DWFC|JV5N1|MADH5

Gene name

SMAD family member 5

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q31

Known cancer genes

Yes

Protein products

Putative uncharacterized protein DKFZp781C1895

MADH5 protein

Mothers against decapentaplegic homolog 5

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:6771
MIM:603110
Ensembl:ENSG00000113658
HPRD:04381
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005057

receptor signaling protein activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006355

regulation of transcription, DNA-dependent

GO:0007165

signal transduction

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0009880

embryonic pattern specification

GO:0016021

integral to membrane

GO:0030509

BMP signaling pathway

GO:0030618

transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity

GO:0031625

ubiquitin protein ligase binding