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Gene basic information

LiverAtlas Gene ID

HuLG002836

Entrez Gene ID

4160

Official Gene Symbol

MC4R

Synonyms

MGC126851|MGC138197

Gene name

melanocortin 4 receptor

Gene Type

protein-coding

Chromosome

18

Genomics Location

18q22

Known cancer genes

Yes

Protein products

Melanocortin 4 receptor variant

Melanocortin 4 receptor variant

Truncated melanocortin 4 receptor variant

Melanocortin 4 receptor variant

Melanocortin receptor 4

Database cross reference

HGNC:6932
MIM:155541
Ensembl:ENSG00000166603
HPRD:01116
RefSeq Genomic nucleotide accession:AC_000061
RefSeq Genomic nucleotide gi:89161196

 

Ontology annotation

GO ID

GO annotation

GO:0002024

diet induced thermogenesis

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0004977

melanocortin receptor activity

GO:0004980

melanocyte-stimulating hormone receptor activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0006112

energy reserve metabolic process

GO:0007188

G-protein signaling, coupled to cAMP nucleotide second messenger

GO:0007631

feeding behavior

GO:0016021

integral to membrane

GO:0017046

peptide hormone binding

GO:0019222

regulation of metabolic process

GO:0030073

insulin secretion

GO:0030819

positive regulation of cAMP biosynthetic process

GO:0031625

ubiquitin protein ligase binding

GO:0032868

response to insulin stimulus

GO:0042923

neuropeptide binding

GO:0045780

positive regulation of bone resorption