HuLG002840

Entrez Gene ID

4168

Official Gene Symbol

MCF2

Synonyms

ARHGEF21|DBL

Gene name

MCF.2 cell line derived transforming sequence

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xq27

Known cancer genes

Yes

Protein products

cDNA, FLJ94537, highly similar to Homo sapiens MCF.2 cell line derived transforming sequence (MCF2), mRNA

cDNA, FLJ79315, highly similar to Proto-oncogene DBL

Uncharacterized protein

Proto-oncogene DBL

MCF.2 cell line derived transforming sequence

Database cross reference

HGNC:6940
MIM:311030
Ensembl:ENSG00000101977
HPRD:02406
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

GO annotation

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005089

Rho guanyl-nucleotide exchange factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005624

membrane fraction

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0006915

apoptosis

GO:0007264

small GTPase mediated signal transduction

GO:0008624

induction of apoptosis by extracellular signals

GO:0016020

membrane

GO:0035023

regulation of Rho protein signal transduction

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051056

regulation of small GTPase mediated signal transduction