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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002883

Entrez Gene ID

4233

Official Gene Symbol

MET

Synonyms

AUTS9|HGFR|RCCP2|cNMet

Gene name

met proto-oncogene (hepatocyte growth factor receptor)

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q31

Known cancer genes

Yes

Protein products

Met proto-oncogene (Hepatocyte growth factor receptor)

Soluble MET variant 1

Soluble MET variant 2

Soluble MET variant 4

Hepatocyte growth factor receptor

Proto-oncogenic met protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:7029
MIM:164860
Ensembl:ENSG00000105976
HPRD:01280
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0004713

protein tyrosine kinase activity

GO:0004872

receptor activity

GO:0005008

hepatocyte growth factor receptor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006468

protein phosphorylation

GO:0007165

signal transduction

GO:0007166

cell surface receptor linked signaling pathway

GO:0007275

multicellular organismal development

GO:0007411

axon guidance

GO:0008283

cell proliferation

GO:0009925

basal plasma membrane

GO:0016021

integral to membrane

GO:0048012

hepatocyte growth factor receptor signaling pathway