Gene basic information
| LiverAtlas Gene ID |
HuLG002900 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
MGMT |
|
Gene name |
O-6-methylguanine-DNA methyltransferase |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10q26 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ56323, highly similar to Methylated-DNA--protein-cysteinemethyltransferase (EC 2.1.1.63) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:7059
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003677 |
DNA binding |
|
GO:0003908 |
methylated-DNA-[protein]-cysteine S-methyltransferase activity |
|
GO:0005509 |
calcium ion binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0006266 |
DNA ligation |
|
GO:0006281 |
DNA repair |
|
GO:0006306 |
DNA methylation |
|
GO:0006307 |
DNA dealkylation involved in DNA repair |
|
GO:0008168 |
methyltransferase activity |
|
GO:0009008 |
DNA-methyltransferase activity |
|
GO:0009636 |
response to toxin |
|
GO:0016740 |
transferase activity |
|
GO:0032259 |
methylation |
|
GO:0034599 |
cellular response to oxidative stress |
|
GO:0042493 |
response to drug |
|
GO:0043281 |
regulation of caspase activity |
|
GO:0045471 |
response to ethanol |
|
GO:0045739 |
positive regulation of DNA repair |
|
GO:0051593 |
response to folic acid |
|
GO:0060548 |
negative regulation of cell death |
|
GO:0060644 |
mammary gland epithelial cell differentiation |
|
GO:0071407 |
cellular response to organic cyclic compound |
|
GO:0071479 |
cellular response to ionizing radiation |
