Gene basic information
LiverAtlas Gene ID |
HuLG002905 |
Entrez Gene ID |
|
Official Gene Symbol |
CIITA |
Synonyms |
C2TA|CIITAIV|MHC2TA|NLRA |
Gene name |
class II, major histocompatibility complex, transactivator |
Gene Type |
protein-coding |
Chromosome |
16 |
Genomics Location |
16p13 |
Known cancer genes |
Yes |
Protein products |
Class II, major histocompatibility complex, transactivator MHC class II transactivator type III Class II, major histocompatibility complex, transactivator, isoform CRA e |
Related liver disease name |
|
Database cross reference |
HGNC:7067
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
GO:0000166 |
nucleotide binding |
GO:0003677 |
DNA binding |
GO:0003713 |
transcription coactivator activity |
GO:0005515 |
protein binding |
GO:0005524 |
ATP binding |
GO:0005634 |
nucleus |
GO:0006355 |
regulation of transcription, DNA-dependent |
GO:0006955 |
immune response |
GO:0008022 |
protein C-terminus binding |
GO:0019221 |
cytokine-mediated signaling pathway |
GO:0032403 |
protein complex binding |
GO:0033613 |
activating transcription factor binding |
GO:0034341 |
response to interferon-gamma |
GO:0045345 |
positive regulation of MHC class I biosynthetic process |
GO:0045348 |
positive regulation of MHC class II biosynthetic process |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046677 |
response to antibiotic |
GO:0060333 |
interferon-gamma-mediated signaling pathway |