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LiverAtlas Gene ID	HuLG002918
Entrez Gene ID	4292
Official Gene Symbol	MLH1
Synonyms	COCA2\|FCC2\|HNPCC\|HNPCC2\|MGC5172\|hMLH1
Gene name	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
Gene Type	protein-coding
Chromosome	3
Genomics Location	3p21.3
Known cancer genes	Yes
Protein products	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), isoform CRA a cDNA FLJ50608, highly similar to DNA mismatch repair protein Mlh1 Uncharacterized protein Uncharacterized protein Uncharacterized protein DNA mismatch repair protein Mlh1 Hypothetical rhabdomyosarcoma antigen MU-RMS-40.5 Mutant mismatch repair protein
Related liver disease name	Hepatitis Viral hepatitis Hepatitis A Hepatitis B Chronic hepatitis B Hepatitis C Hepatitis D Hepatitis E Chronic hepatitis Hepatocellular carcinoma Intrahepatic cholangiocarcinoma Hepatocellular carcinoma
Database cross reference	HGNC:7127 MIM:120436 Ensembl:ENSG00000076242 HPRD:00390 RefSeq Genomic nucleotide accession:AC_000046 RefSeq Genomic nucleotide gi:89161204

GO ID	GO annotation
GO:0000239	pachytene
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
GO:0000712	resolution of meiotic recombination intermediates
GO:0000795	synaptonemal complex
GO:0001673	male germ cell nucleus
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005634	nucleus
GO:0005712	chiasma
GO:0006200	ATP catabolic process
GO:0006298	mismatch repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0007049	cell cycle
GO:0007060	male meiosis chromosome segregation
GO:0007131	reciprocal meiotic recombination
GO:0007283	spermatogenesis
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0016446	somatic hypermutation of immunoglobulin genes
GO:0016887	ATPase activity
GO:0030983	mismatched DNA binding
GO:0032137	guanine/thymine mispair binding
GO:0032389	MutLalpha complex
GO:0032390	MutLbeta complex
GO:0032407	MutSalpha complex binding
GO:0043060	meiotic metaphase I plate congression
GO:0045190	isotype switching
GO:0045950	negative regulation of mitotic recombination
GO:0048477	oogenesis
GO:0051257	spindle midzone assembly involved in meiosis