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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002930

Entrez Gene ID

4306

Official Gene Symbol

NR3C2

Synonyms

FLJ41052|MCR|MGC133092|MLR|MR|NR3C2VIT

Gene name

nuclear receptor subfamily 3, group C, member 2

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q31.1

Known cancer genes

Yes

Protein products

Mineralocorticoid receptor 1

Mineralocorticoid receptor

Mineralocorticoid receptor

NR3C2 protein

Putative uncharacterized protein NR3C2

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:7979
MIM:600983
Ensembl:ENSG00000151623
HPRD:02991
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003707

steroid hormone receptor activity

GO:0004872

receptor activity

GO:0005496

steroid binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0007165

signal transduction

GO:0008270

zinc ion binding

GO:0010467

gene expression

GO:0016020

membrane

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0043401

steroid hormone mediated signaling pathway

GO:0043565

sequence-specific DNA binding

GO:0046872

metal ion binding