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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002933

Entrez Gene ID

4312

Official Gene Symbol

MMP1

Synonyms

CLG|CLGN

Gene name

matrix metallopeptidase 1 (interstitial collagenase)

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q22.3

Known cancer genes

Yes

Protein products

cDNA FLJ55228, highly similar to Interstitial collagenase (EC 3.4.24.7)

Interstitial collagenase

Matrix metalloproteinase 1 preproprotein variant

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Hepatocellular carcinoma

Database cross reference

HGNC:7155
MIM:120353
Ensembl:ENSG00000196611
HPRD:00384
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004222

metalloendopeptidase activity

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0006508

proteolysis

GO:0007596

blood coagulation

GO:0008152

metabolic process

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0030574

collagen catabolic process

GO:0044419

interspecies interaction between organisms

GO:0050900

leukocyte migration