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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002934

Entrez Gene ID

4313

Official Gene Symbol

MMP2

Synonyms

CLG4|CLG4A|MMPNII|MONA|TBEN1

Gene name

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q13-q21

Known cancer genes

Yes

Protein products

Uncharacterized protein

72 kDa type IV collagenase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:7166
MIM:120360
Ensembl:ENSG00000087245
HPRD:00386
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001525

angiogenesis

GO:0004222

metalloendopeptidase activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0006508

proteolysis

GO:0008152

metabolic process

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0016020

membrane

GO:0030574

collagen catabolic process

GO:0043231

intracellular membrane-bounded organelle

GO:0046872

metal ion binding