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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002935

Entrez Gene ID

4314

Official Gene Symbol

MMP3

Synonyms

CHDS6|MGC126102|MGC126103|MGC126104|MMPN3|SLN1|STMY|STMY1|STR1

Gene name

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q22.3

Known cancer genes

Yes

Protein products

Matrix metalloproteinase 3

Stromelysin-1

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis B infection

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:7173
MIM:185250
Ensembl:ENSG00000149968
HPRD:01703
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0004222

metalloendopeptidase activity

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0006508

proteolysis

GO:0007565

female pregnancy

GO:0008152

metabolic process

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0030425

dendrite

GO:0030574

collagen catabolic process

GO:0032355

response to estradiol stimulus

GO:0032403

protein complex binding

GO:0032496

response to lipopolysaccharide

GO:0034612

response to tumor necrosis factor

GO:0042060

wound healing

GO:0043200

response to amino acid stimulus

GO:0043231

intracellular membrane-bounded organelle

GO:0043234

protein complex

GO:0044297

cell body

GO:0070555

response to interleukin-1

GO:0071460

cellular response to cell-matrix adhesion