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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002936

Entrez Gene ID

4316

Official Gene Symbol

MMP7

Synonyms

MMPN7|MPSL1|PUMPN1

Gene name

matrix metallopeptidase 7 (matrilysin, uterine)

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q21-q22

Known cancer genes

Yes

Protein products

Matrix metalloproteinase 7

Matrilysin

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:7174
MIM:178990
Ensembl:ENSG00000137673
HPRD:01525
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002779

antibacterial peptide secretion

GO:0004222

metalloendopeptidase activity

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0006508

proteolysis

GO:0008152

metabolic process

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0030574

collagen catabolic process

GO:0042127

regulation of cell proliferation

GO:0042493

response to drug

GO:0046872

metal ion binding

GO:0050829

defense response to Gram-negative bacterium

GO:0050830

defense response to Gram-positive bacterium