HuLG002937

Entrez Gene ID

4317

Official Gene Symbol

MMP8

Synonyms

CLG1|HNC|MMPN8|PMNLNCL

Gene name

matrix metallopeptidase 8 (neutrophil collagenase)

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q22.3

Known cancer genes

Yes

Protein products

Neutrophil collagenase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:7175
MIM:120355
Ensembl:ENSG00000118113
HPRD:00385
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

GO annotation

GO:0001503

ossification

GO:0004222

metalloendopeptidase activity

GO:0004252

serine-type endopeptidase activity

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0006508

proteolysis

GO:0008152

metabolic process

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0030574

collagen catabolic process