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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002940

Entrez Gene ID

4320

Official Gene Symbol

MMP11

Synonyms

SLN3|ST3|STMY3

Gene name

matrix metallopeptidase 11 (stromelysin 3)

Gene Type

protein-coding

Chromosome

22

Genomics Location

22q11.2|22q11.23

Known cancer genes

Yes

Protein products

Matrix metallopeptidase 11 (Stromelysin 3), isoform CRA b

Stromelysin-3

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:7157
MIM:185261
Ensembl:ENSG00000099953
HPRD:01705
RefSeq Genomic nucleotide accession:AC_000065
RefSeq Genomic nucleotide gi:89161202

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004222

metalloendopeptidase activity

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0006508

proteolysis

GO:0007275

multicellular organismal development

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0030574

collagen catabolic process