Gene basic information
| LiverAtlas Gene ID |
HuLG002943 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
MMP14 |
|
Synonyms |
MMPNX1|MT1NMMP|MTMMP1 |
|
Gene name |
matrix metallopeptidase 14 (membrane-inserted) |
|
Gene Type |
protein-coding |
|
Chromosome |
14 |
|
Genomics Location |
14q11-q12 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:7160
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001503 |
ossification |
|
GO:0001525 |
angiogenesis |
|
GO:0001541 |
ovarian follicle development |
|
GO:0001666 |
response to hypoxia |
|
GO:0001935 |
endothelial cell proliferation |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0004222 |
metalloendopeptidase activity |
|
GO:0005178 |
integrin binding |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006508 |
proteolysis |
|
GO:0006979 |
response to oxidative stress |
|
GO:0008152 |
metabolic process |
|
GO:0008270 |
zinc ion binding |
|
GO:0009612 |
response to mechanical stimulus |
|
GO:0009725 |
response to hormone stimulus |
|
GO:0014070 |
response to organic cyclic compound |
|
GO:0016020 |
membrane |
|
GO:0016477 |
cell migration |
|
GO:0016504 |
peptidase activator activity |
|
GO:0030324 |
lung development |
|
GO:0031012 |
extracellular matrix |
|
GO:0031638 |
zymogen activation |
|
GO:0042470 |
melanosome |
|
GO:0043615 |
astrocyte cell migration |
|
GO:0043627 |
response to estrogen stimulus |
|
GO:0048754 |
branching morphogenesis of a tube |
|
GO:0048771 |
tissue remodeling |
|
GO:0051895 |
negative regulation of focal adhesion assembly |
