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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002944

Entrez Gene ID

4324

Official Gene Symbol

MMP15

Synonyms

MT2NMMP|MTMMP2|SMCPN2

Gene name

matrix metallopeptidase 15 (membrane-inserted)

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q13

Known cancer genes

Yes

Protein products

Matrix metalloproteinase-15

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis C infection

Database cross reference

HGNC:7161
MIM:602261
Ensembl:ENSG00000102996
HPRD:03775
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004222

metalloendopeptidase activity

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0005887

integral to plasma membrane

GO:0006464

protein modification process

GO:0006508

proteolysis

GO:0008047

enzyme activator activity

GO:0008152

metabolic process

GO:0008233

peptidase activity

GO:0008270

zinc ion binding

GO:0016020

membrane

GO:0031012

extracellular matrix

GO:0043085

positive regulation of catalytic activity