Home - LiverAtlas

Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease.

LiverAtlas Gene ID	HuLG003010
Entrez Gene ID	4524
Official Gene Symbol	MTHFR
Gene name	methylenetetrahydrofolate reductase (NAD(P)H)
Gene Type	protein-coding
Chromosome	1
Genomics Location	1p36.3
Known cancer genes	Yes
Protein products	Methylenetetrahydrofolate reductase Methylenetetrahydrofolate reductase Methylenetetrahydrofolate reductase 5,10-methylenetetrahydrofolate reductase (NADPH) Methylenetetrahydrofolate reductase long isoform
Related liver disease name	Hepatitis Liver fibrosis and liver cirrhosis Viral hepatitis Hepatitis A Hepatitis B Hepatitis C Chronic hepatitis C Hepatitis D Hepatitis E Chronic hepatitis Drug-induced hepatitis Alcoholic liver cirrhosis Hepatocellular carcinoma Primary biliary cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection Intrahepatic cholangiocarcinoma Nonalcoholic steatohepatitis
Database cross reference	HGNC:7436 MIM:607093 Ensembl:ENSG00000177000 HPRD:06158 RefSeq Genomic nucleotide accession:AC_000044 RefSeq Genomic nucleotide gi:89161184

GO ID	GO annotation
GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity
GO:0005515	protein binding
GO:0005829	cytosol
GO:0006520	cellular amino acid metabolic process
GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process
GO:0008015	blood circulation
GO:0009086	methionine biosynthetic process
GO:0016491	oxidoreductase activity
GO:0046655	folic acid metabolic process