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Gene basic information

LiverAtlas Gene ID

HuLG003139

Entrez Gene ID

4719

Official Gene Symbol

NDUFS1

Synonyms

CIN75Kd|CIN75k|MGC26839|PRO1304

Gene name

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q33-q34

Known cancer genes

Yes

Protein products

cDNA FLJ54000, highly similar to NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3)

NADH-ubiquinone oxidoreductase 75 kDa subunit

cDNA FLJ55879, highly similar to NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3)

cDNA FLJ53201, highly similar to NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3)

NADH-ubiquinone oxidoreductase 75 kDa subunit

Uncharacterized protein

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

Database cross reference

HGNC:7707
MIM:157655
Ensembl:ENSG00000023228
HPRD:01145
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

 

Ontology annotation

GO ID

GO annotation

GO:0003954

NADH dehydrogenase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0005747

mitochondrial respiratory chain complex I

GO:0005758

mitochondrial intermembrane space

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

GO:0006810

transport

GO:0006915

apoptosis

GO:0008137

NADH dehydrogenase (ubiquinone) activity

GO:0009055

electron carrier activity

GO:0016020

membrane

GO:0022904

respiratory electron transport chain

GO:0042773

ATP synthesis coupled electron transport

GO:0045333

cellular respiration

GO:0046034

ATP metabolic process

GO:0046872

metal ion binding

GO:0051537

2 iron, 2 sulfur cluster binding

GO:0051539

4 iron, 4 sulfur cluster binding

GO:0051881

regulation of mitochondrial membrane potential

GO:0070469

respiratory chain

GO:0072593

reactive oxygen species metabolic process