Gene basic information
LiverAtlas Gene ID |
HuLG003139 |
Entrez Gene ID |
|
Official Gene Symbol |
NDUFS1 |
Synonyms |
CIN75Kd|CIN75k|MGC26839|PRO1304 |
Gene name |
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) |
Gene Type |
protein-coding |
Chromosome |
2 |
Genomics Location |
2q33-q34 |
Known cancer genes |
Yes |
Protein products |
NADH-ubiquinone oxidoreductase 75 kDa subunit NADH-ubiquinone oxidoreductase 75 kDa subunit NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
Database cross reference |
HGNC:7707
|
Ontology annotation
GO ID |
GO annotation |
GO:0003954 |
NADH dehydrogenase activity |
GO:0005515 |
protein binding |
GO:0005739 |
mitochondrion |
GO:0005743 |
mitochondrial inner membrane |
GO:0005747 |
mitochondrial respiratory chain complex I |
GO:0005758 |
mitochondrial intermembrane space |
GO:0006120 |
mitochondrial electron transport, NADH to ubiquinone |
GO:0006810 |
transport |
GO:0006915 |
apoptosis |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
GO:0009055 |
electron carrier activity |
GO:0016020 |
membrane |
GO:0022904 |
respiratory electron transport chain |
GO:0042773 |
ATP synthesis coupled electron transport |
GO:0045333 |
cellular respiration |
GO:0046034 |
ATP metabolic process |
GO:0046872 |
metal ion binding |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
GO:0051881 |
regulation of mitochondrial membrane potential |
GO:0070469 |
respiratory chain |
GO:0072593 |
reactive oxygen species metabolic process |