Gene basic information
| LiverAtlas Gene ID |
HuLG003150 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
NEDD4 |
|
Synonyms |
KIAA0093|MGC176705|NEDD4N1|RPF1 |
|
Gene name |
neural precursor cell expressed, developmentally down-regulated 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
15 |
|
Genomics Location |
15q |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:7727
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000151 |
ubiquitin ligase complex |
|
GO:0000785 |
chromatin |
|
GO:0004842 |
ubiquitin-protein ligase activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005624 |
membrane fraction |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0005938 |
cell cortex |
|
GO:0006464 |
protein modification process |
|
GO:0006622 |
protein targeting to lysosome |
|
GO:0007041 |
lysosomal transport |
|
GO:0007399 |
nervous system development |
|
GO:0010766 |
negative regulation of sodium ion transport |
|
GO:0010768 |
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage |
|
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
|
GO:0016327 |
apicolateral plasma membrane |
|
GO:0016567 |
protein ubiquitination |
|
GO:0016874 |
ligase activity |
|
GO:0016881 |
acid-amino acid ligase activity |
|
GO:0019089 |
transmission of virus |
|
GO:0019871 |
sodium channel inhibitor activity |
|
GO:0019904 |
protein domain specific binding |
|
GO:0030948 |
negative regulation of vascular endothelial growth factor receptor signaling pathway |
|
GO:0031175 |
neuron projection development |
|
GO:0031623 |
receptor internalization |
|
GO:0031698 |
beta-2 adrenergic receptor binding |
|
GO:0032801 |
receptor catabolic process |
|
GO:0034644 |
cellular response to UV |
|
GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
|
GO:0042921 |
glucocorticoid receptor signaling pathway |
|
GO:0043130 |
ubiquitin binding |
|
GO:0044111 |
development involved in symbiotic interaction |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045732 |
positive regulation of protein catabolic process |
|
GO:0046824 |
positive regulation of nucleocytoplasmic transport |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048814 |
regulation of dendrite morphogenesis |
|
GO:0050815 |
phosphoserine binding |
|
GO:0050816 |
phosphothreonine binding |
|
GO:0050847 |
progesterone receptor signaling pathway |
|
GO:0051592 |
response to calcium ion |
|
GO:0070063 |
RNA polymerase binding |
|
GO:0070064 |
proline-rich region binding |
|
GO:0070534 |
protein K63-linked ubiquitination |
