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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003160

Entrez Gene ID

4751

Official Gene Symbol

NEK2

Synonyms

HsPK21|NEK2A|NLK1

Gene name

NIMA (never in mitosis gene a)-related kinase 2

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q32.2-q41

Known cancer genes

Yes

Protein products

Serine/threonine-protein kinase Nek2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:7745
MIM:604043
Ensembl:ENSG00000117650
HPRD:04953
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000070

mitotic sister chromatid segregation

GO:0000086

G2/M transition of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000278

mitotic cell cycle

GO:0000776

kinetochore

GO:0000777

condensed chromosome kinetochore

GO:0000794

condensed nuclear chromosome

GO:0000922

spindle pole

GO:0004672

protein kinase activity

GO:0004674

protein serine/threonine kinase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005694

chromosome

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005813

centrosome

GO:0005829

cytosol

GO:0007059

chromosome segregation

GO:0007067

mitosis

GO:0007088

regulation of mitosis

GO:0007126

meiosis

GO:0019903

protein phosphatase binding

GO:0030496

midbody

GO:0043234

protein complex

GO:0046777

protein autophosphorylation

GO:0046872

metal ion binding

GO:0051299

centrosome separation

GO:0051301

cell division