Gene basic information
LiverAtlas Gene ID |
HuLG003169 |
Entrez Gene ID |
|
Official Gene Symbol |
NF2 |
Synonyms |
ACN|BANF|SCH |
Gene name |
neurofibromin 2 (merlin) |
Gene Type |
protein-coding |
Chromosome |
22 |
Genomics Location |
22q12.2 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:7773
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001707 |
mesoderm formation |
GO:0001953 |
negative regulation of cell-matrix adhesion |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005730 |
nucleolus |
GO:0005737 |
cytoplasm |
GO:0005769 |
early endosome |
GO:0005856 |
cytoskeleton |
GO:0005886 |
plasma membrane |
GO:0005912 |
adherens junction |
GO:0006469 |
negative regulation of protein kinase activity |
GO:0007398 |
ectoderm development |
GO:0008092 |
cytoskeletal protein binding |
GO:0008156 |
negative regulation of DNA replication |
GO:0008285 |
negative regulation of cell proliferation |
GO:0014010 |
Schwann cell proliferation |
GO:0019898 |
extrinsic to membrane |
GO:0022408 |
negative regulation of cell-cell adhesion |
GO:0030027 |
lamellipodium |
GO:0030036 |
actin cytoskeleton organization |
GO:0030336 |
negative regulation of cell migration |
GO:0031527 |
filopodium membrane |
GO:0032154 |
cleavage furrow |
GO:0032587 |
ruffle membrane |
GO:0035330 |
regulation of hippo signaling cascade |
GO:0042475 |
odontogenesis of dentine-containing tooth |
GO:0042518 |
negative regulation of tyrosine phosphorylation of Stat3 protein |
GO:0042524 |
negative regulation of tyrosine phosphorylation of Stat5 protein |
GO:0043409 |
negative regulation of MAPKKK cascade |
GO:0045216 |
cell-cell junction organization |
GO:0046426 |
negative regulation of JAK-STAT cascade |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0051496 |
positive regulation of stress fiber assembly |
GO:0070306 |
lens fiber cell differentiation |