HuLG003183

Entrez Gene ID

4791

Official Gene Symbol

NFKB2

Synonyms

LYTN10|LYT10|p52

Gene name

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24

Known cancer genes

Yes

Protein products

Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (P49/p100), isoform CRA a

Nuclear factor NF-kappa-B p100 subunit

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:7795
MIM:164012
Ensembl:ENSG00000077150
HPRD:01239
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

GO annotation

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003713

transcription coactivator activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0007165

signal transduction

GO:0008063

Toll signaling pathway

GO:0033257

Bcl3/NF-kappaB2 complex

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0045087

innate immune response

GO:0051092

positive regulation of NF-kappaB transcription factor activity