Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003221

Entrez Gene ID

4842

Official Gene Symbol

NOS1

Synonyms

IHPS1|NNNOS|NCNNOS|NOS|bNOS|nNOS

Gene name

nitric oxide synthase 1 (neuronal)

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.2-q24.31

Known cancer genes

Yes

Protein products

NOS1 protein

NOS1 mutant

cDNA FLJ57045, highly similar to Nitric-oxide synthase, brain (EC 1.14.13.39)

Uncharacterized protein

Nitric oxide synthase, brain

Neuronal nitric-oxide synthase isoform mu

Database cross reference

HGNC:7872
MIM:163731
Ensembl:ENSG00000089250
HPRD:01226
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0001917

photoreceptor inner segment

GO:0002028

regulation of sodium ion transport

GO:0004517

nitric-oxide synthase activity

GO:0005515

protein binding

GO:0005516

calmodulin binding

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0006527

arginine catabolic process

GO:0006809

nitric oxide biosynthetic process

GO:0006941

striated muscle contraction

GO:0007520

myoblast fusion

GO:0007596

blood coagulation

GO:0009408

response to heat

GO:0010181

FMN binding

GO:0010523

negative regulation of calcium ion transport into cytosol

GO:0016491

oxidoreductase activity

GO:0016529

sarcoplasmic reticulum

GO:0018119

peptidyl-cysteine S-nitrosylation

GO:0020037

heme binding

GO:0030168

platelet activation

GO:0033555

multicellular organismal response to stress

GO:0034617

tetrahydrobiopterin binding

GO:0034618

arginine binding

GO:0035066

positive regulation of histone acetylation

GO:0042136

neurotransmitter biosynthetic process

GO:0042383

sarcolemma

GO:0042738

exogenous drug catabolic process

GO:0042995

cell projection

GO:0043197

dendritic spine

GO:0043267

negative regulation of potassium ion transport

GO:0045202

synapse

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045909

positive regulation of vasodilation

GO:0046870

cadmium ion binding

GO:0046872

metal ion binding

GO:0048471

perinuclear region of cytoplasm

GO:0050660

flavin adenine dinucleotide binding

GO:0050661

NADP binding

GO:0051346

negative regulation of hydrolase activity

GO:0051612

negative regulation of serotonin uptake

GO:0055117

regulation of cardiac muscle contraction

GO:0071363

cellular response to growth factor stimulus