Gene basic information
| LiverAtlas Gene ID |
HuLG003239 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
NPC1 |
|
Synonyms |
FLJ98532|NPC |
|
Gene name |
Niemann-Pick disease, type C1 |
|
Gene Type |
protein-coding |
|
Chromosome |
18 |
|
Genomics Location |
18q11-q12 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:7897
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004872 |
receptor activity |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005635 |
nuclear envelope |
|
GO:0005764 |
lysosome |
|
GO:0005765 |
lysosomal membrane |
|
GO:0005768 |
endosome |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006897 |
endocytosis |
|
GO:0006914 |
autophagy |
|
GO:0007041 |
lysosomal transport |
|
GO:0007628 |
adult walking behavior |
|
GO:0008158 |
hedgehog receptor activity |
|
GO:0008206 |
bile acid metabolic process |
|
GO:0015248 |
sterol transporter activity |
|
GO:0015918 |
sterol transport |
|
GO:0016021 |
integral to membrane |
|
GO:0016242 |
negative regulation of macroautophagy |
|
GO:0031902 |
late endosome membrane |
|
GO:0031982 |
vesicle |
|
GO:0033344 |
cholesterol efflux |
|
GO:0042493 |
response to drug |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0045121 |
membrane raft |
|
GO:0046686 |
response to cadmium ion |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0071383 |
cellular response to steroid hormone stimulus |
|
GO:0071404 |
cellular response to low-density lipoprotein particle stimulus |
