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Gene basic information

LiverAtlas Gene ID

HuLG003244

Entrez Gene ID

4879

Official Gene Symbol

NPPB

Synonyms

BNP

Gene name

natriuretic peptide B

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.2

Known cancer genes

Yes

Protein products

Natriuretic peptides B

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:7940
MIM:600295
Ensembl:ENSG00000120937
HPRD:08974
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0005102

receptor binding

GO:0005179

hormone activity

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006182

cGMP biosynthetic process

GO:0006954

inflammatory response

GO:0007166

cell surface receptor linked signaling pathway

GO:0007168

receptor guanylyl cyclase signaling pathway

GO:0007507

heart development

GO:0007589

body fluid secretion

GO:0008217

regulation of blood pressure

GO:0008613

diuretic hormone activity

GO:0014070

response to organic cyclic compound

GO:0016525

negative regulation of angiogenesis

GO:0030308

negative regulation of cell growth

GO:0042312

regulation of vasodilation

GO:0042493

response to drug

GO:0043114

regulation of vascular permeability

GO:0043434

response to peptide hormone stimulus

GO:0048471

perinuclear region of cytoplasm

GO:0048662

negative regulation of smooth muscle cell proliferation

GO:0050880

regulation of blood vessel size

GO:0051428

peptide hormone receptor binding

GO:0051592

response to calcium ion