Gene basic information
| LiverAtlas Gene ID |
HuLG003254 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SLC11A2 |
|
Synonyms |
DCT1|DMT1|FLJ37416|NRAMP2 |
|
Gene name |
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q13 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ54692, highly similar to Natural resistance-associated macrophage protein 2 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:10908
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001666 |
response to hypoxia |
|
GO:0003032 |
detection of oxygen |
|
GO:0005215 |
transporter activity |
|
GO:0005375 |
copper ion transmembrane transporter activity |
|
GO:0005381 |
iron ion transmembrane transporter activity |
|
GO:0005384 |
manganese ion transmembrane transporter activity |
|
GO:0005385 |
zinc ion transmembrane transporter activity |
|
GO:0005506 |
iron ion binding |
|
GO:0005507 |
copper ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005764 |
lysosome |
|
GO:0005765 |
lysosomal membrane |
|
GO:0005769 |
early endosome |
|
GO:0005770 |
late endosome |
|
GO:0005773 |
vacuole |
|
GO:0005802 |
trans-Golgi network |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0005903 |
brush border |
|
GO:0006783 |
heme biosynthetic process |
|
GO:0006811 |
ion transport |
|
GO:0006824 |
cobalt ion transport |
|
GO:0006825 |
copper ion transport |
|
GO:0006828 |
manganese ion transport |
|
GO:0006879 |
cellular iron ion homeostasis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0007611 |
learning or memory |
|
GO:0008270 |
zinc ion binding |
|
GO:0009986 |
cell surface |
|
GO:0010039 |
response to iron ion |
|
GO:0010042 |
response to manganese ion |
|
GO:0010288 |
response to lead ion |
|
GO:0012505 |
endomembrane system |
|
GO:0015078 |
hydrogen ion transmembrane transporter activity |
|
GO:0015085 |
calcium ion transmembrane transporter activity |
|
GO:0015086 |
cadmium ion transmembrane transporter activity |
|
GO:0015087 |
cobalt ion transmembrane transporter activity |
|
GO:0015093 |
ferrous iron transmembrane transporter activity |
|
GO:0015094 |
lead ion transmembrane transporter activity |
|
GO:0015099 |
nickel ion transmembrane transporter activity |
|
GO:0015100 |
vanadium ion transmembrane transporter activity |
|
GO:0015295 |
solute:hydrogen symporter activity |
|
GO:0015675 |
nickel ion transport |
|
GO:0015676 |
vanadium ion transport |
|
GO:0015684 |
ferrous iron transport |
|
GO:0015692 |
lead ion transport |
|
GO:0015992 |
proton transport |
|
GO:0016151 |
nickel ion binding |
|
GO:0016324 |
apical plasma membrane |
|
GO:0022890 |
inorganic cation transmembrane transporter activity |
|
GO:0030145 |
manganese ion binding |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0031902 |
late endosome membrane |
|
GO:0034599 |
cellular response to oxidative stress |
|
GO:0034755 |
iron ion transmembrane transport |
|
GO:0035434 |
copper ion transmembrane transport |
|
GO:0035444 |
nickel ion transmembrane transport |
|
GO:0045177 |
apical part of cell |
|
GO:0045178 |
basal part of cell |
|
GO:0046686 |
response to cadmium ion |
|
GO:0046870 |
cadmium ion binding |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048813 |
dendrite morphogenesis |
|
GO:0048821 |
erythrocyte development |
|
GO:0050897 |
cobalt ion binding |
|
GO:0055037 |
recycling endosome |
|
GO:0055085 |
transmembrane transport |
|
GO:0060586 |
multicellular organismal iron ion homeostasis |
|
GO:0070574 |
cadmium ion transmembrane transport |
|
GO:0070627 |
ferrous iron import |
|
GO:0070826 |
paraferritin complex |
|
GO:0070835 |
chromium ion transmembrane transporter activity |
|
GO:0071421 |
manganese ion transmembrane transport |
|
GO:0071577 |
zinc ion transmembrane transport |
