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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003265

Entrez Gene ID

4907

Official Gene Symbol

NT5E

Synonyms

CD73|E5NT|NT|NT5|NTE|eN|eNT

Gene name

5'-nucleotidase, ecto (CD73)

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q14-q21

Known cancer genes

Yes

Protein products

5'-nucleotidase

cDNA FLJ90527 fis, clone NT2RP4001467, highly similar to 5'-nucleotidase (EC 3.1.3.5)

Uncharacterized protein

5'-nucleotidase

5'-nucleotidase, ecto (CD73)

5'-nucleotidase, ecto (CD73)

5'-nucleotidase, ecto (CD73)

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:8021
MIM:129190
Ensembl:ENSG00000135318
HPRD:00552
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0005624

membrane fraction

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006144

purine base metabolic process

GO:0006164

purine nucleotide biosynthetic process

GO:0006195

purine nucleotide catabolic process

GO:0006196

AMP catabolic process

GO:0006206

pyrimidine base metabolic process

GO:0006259

DNA metabolic process

GO:0008198

ferrous iron binding

GO:0008253

5'-nucleotidase activity

GO:0016788

hydrolase activity, acting on ester bonds

GO:0031225

anchored to membrane

GO:0046086

adenosine biosynthetic process

GO:0046135

pyrimidine nucleoside catabolic process

GO:0046872

metal ion binding

GO:0050728

negative regulation of inflammatory response

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process