Gene basic information
LiverAtlas Gene ID |
HuLG003265 |
Entrez Gene ID |
|
Official Gene Symbol |
NT5E |
Synonyms |
CD73|E5NT|NT|NT5|NTE|eN|eNT |
Gene name |
5'-nucleotidase, ecto (CD73) |
Gene Type |
protein-coding |
Chromosome |
6 |
Genomics Location |
6q14-q21 |
Known cancer genes |
Yes |
Protein products |
cDNA FLJ90527 fis, clone NT2RP4001467, highly similar to 5'-nucleotidase (EC 3.1.3.5) |
Related liver disease name |
|
Database cross reference |
HGNC:8021
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0005624 |
membrane fraction |
GO:0005737 |
cytoplasm |
GO:0005886 |
plasma membrane |
GO:0006144 |
purine base metabolic process |
GO:0006164 |
purine nucleotide biosynthetic process |
GO:0006195 |
purine nucleotide catabolic process |
GO:0006196 |
AMP catabolic process |
GO:0006206 |
pyrimidine base metabolic process |
GO:0006259 |
DNA metabolic process |
GO:0008198 |
ferrous iron binding |
GO:0008253 |
5'-nucleotidase activity |
GO:0016788 |
hydrolase activity, acting on ester bonds |
GO:0031225 |
anchored to membrane |
GO:0046086 |
adenosine biosynthetic process |
GO:0046135 |
pyrimidine nucleoside catabolic process |
GO:0046872 |
metal ion binding |
GO:0050728 |
negative regulation of inflammatory response |
GO:0055086 |
nucleobase, nucleoside and nucleotide metabolic process |