Gene basic information
| LiverAtlas Gene ID |
HuLG003286 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
OAS1 |
|
Synonyms |
IFIN4|OIAS|OIASI |
|
Gene name |
2',5'-oligoadenylate synthetase 1, 40/46kDa |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q24.1 |
|
Known cancer genes |
Yes |
|
Protein products |
2'-5' oligoadenylate synthetase 1 p41 isoform |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:8086
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0003723 |
RNA binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005792 |
microsome |
|
GO:0006139 |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
|
GO:0006955 |
immune response |
|
GO:0016740 |
transferase activity |
|
GO:0016779 |
nucleotidyltransferase activity |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0060333 |
interferon-gamma-mediated signaling pathway |
|
GO:0060337 |
type I interferon-mediated signaling pathway |
