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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003287

Entrez Gene ID

4939

Official Gene Symbol

OAS2

Synonyms

MGC78578

Gene name

2'-5'-oligoadenylate synthetase 2, 69/71kDa

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.2

Known cancer genes

Yes

Protein products

2'-5'-oligoadenylate synthase 2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

2'-5'-oligoadenylate synthetase 2, 69/71kDa

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:8087
MIM:603350
Ensembl:ENSG00000111335
HPRD:04518
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003723

RNA binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005739

mitochondrion

GO:0005783

endoplasmic reticulum

GO:0005792

microsome

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

GO:0006955

immune response

GO:0016020

membrane

GO:0016740

transferase activity

GO:0016779

nucleotidyltransferase activity

GO:0019221

cytokine-mediated signaling pathway

GO:0060333

interferon-gamma-mediated signaling pathway

GO:0060337

type I interferon-mediated signaling pathway