Gene basic information
| LiverAtlas Gene ID |
HuLG003301 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
OGG1 |
|
Synonyms |
HMMH|HOGG1|MUTM|OGH1 |
|
Gene name |
8-oxoguanine DNA glycosylase |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p26.2 |
|
Known cancer genes |
Yes |
|
Protein products |
8-oxoguanine DNA glycosylase, isoform CRA a 8-oxoguanine DNA glycosylase, isoform CRA k 8-oxoguanine DNA glycosylase, isoform CRA j 8-oxoguanine DNA glycosylase, isoform CRA e 8-oxoguanine DNA glycosylase, isoform CRA h 8-oxoguanine DNA glycosylase, isoform CRA d 8-oxoguanine DNA glycosylase, isoform CRA f |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8125
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003684 |
damaged DNA binding |
|
GO:0004519 |
endonuclease activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0006281 |
DNA repair |
|
GO:0006284 |
base-excision repair |
|
GO:0006285 |
base-excision repair, AP site formation |
|
GO:0006289 |
nucleotide-excision repair |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006979 |
response to oxidative stress |
|
GO:0008534 |
oxidized purine base lesion DNA N-glycosylase activity |
|
GO:0009314 |
response to radiation |
|
GO:0016363 |
nuclear matrix |
|
GO:0016607 |
nuclear speck |
|
GO:0016798 |
hydrolase activity, acting on glycosyl bonds |
|
GO:0016829 |
lyase activity |
|
GO:0033158 |
regulation of protein import into nucleus, translocation |
|
GO:0045007 |
depurination |
