Gene basic information
| LiverAtlas Gene ID |
HuLG003350 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
P4HA1 |
|
Synonyms |
P4HA |
|
Gene name |
prolyl 4-hydroxylase, alpha polypeptide I |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10q21.3-q23.1 |
|
Known cancer genes |
Yes |
|
Protein products |
Prolyl 4-hydroxylase subunit alpha-1 Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), alpha polypeptide I |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8546
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004656 |
procollagen-proline 4-dioxygenase activity |
|
GO:0005488 |
binding |
|
GO:0005506 |
iron ion binding |
|
GO:0005739 |
mitochondrion |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005788 |
endoplasmic reticulum lumen |
|
GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
|
GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
|
GO:0018401 |
peptidyl-proline hydroxylation to 4-hydroxy-L-proline |
|
GO:0030199 |
collagen fibril organization |
|
GO:0031418 |
L-ascorbic acid binding |
|
GO:0043231 |
intracellular membrane-bounded organelle |
|
GO:0046872 |
metal ion binding |
