Gene basic information
| LiverAtlas Gene ID |
HuLG003356 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PCSK6 |
|
Synonyms |
PACE4|SPC4 |
|
Gene name |
proprotein convertase subtilisin/kexin type 6 |
|
Gene Type |
protein-coding |
|
Chromosome |
15 |
|
Genomics Location |
15q26.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8569
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004175 |
endopeptidase activity |
|
GO:0004252 |
serine-type endopeptidase activity |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005625 |
soluble fraction |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005796 |
Golgi lumen |
|
GO:0007354 |
zygotic determination of anterior/posterior axis, embryo |
|
GO:0007368 |
determination of left/right symmetry |
|
GO:0008201 |
heparin binding |
|
GO:0008233 |
peptidase activity |
|
GO:0009100 |
glycoprotein metabolic process |
|
GO:0009986 |
cell surface |
|
GO:0012505 |
endomembrane system |
|
GO:0016020 |
membrane |
|
GO:0016486 |
peptide hormone processing |
|
GO:0030510 |
regulation of BMP signaling pathway |
|
GO:0031012 |
extracellular matrix |
|
GO:0032455 |
nerve growth factor processing |
|
GO:0032902 |
nerve growth factor production |
|
GO:0032940 |
secretion by cell |
|
GO:0043499 |
eukaryotic cell surface binding |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0048406 |
nerve growth factor binding |
|
GO:0051605 |
protein maturation by peptide bond cleavage |
