Gene basic information
| LiverAtlas Gene ID |
HuLG003363 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PAH |
|
Synonyms |
PH|PKU|PKU1 |
|
Gene name |
phenylalanine hydroxylase |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q22-q24.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8582
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004505 |
phenylalanine 4-monooxygenase activity |
|
GO:0005506 |
iron ion binding |
|
GO:0005829 |
cytosol |
|
GO:0006559 |
L-phenylalanine catabolic process |
|
GO:0006571 |
tyrosine biosynthetic process |
|
GO:0008652 |
cellular amino acid biosynthetic process |
|
GO:0016597 |
amino acid binding |
|
GO:0018126 |
protein hydroxylation |
|
GO:0034641 |
cellular nitrogen compound metabolic process |
|
GO:0042136 |
neurotransmitter biosynthetic process |
|
GO:0042423 |
catecholamine biosynthetic process |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0046146 |
tetrahydrobiopterin metabolic process |
|
GO:0046872 |
metal ion binding |
|
GO:0048037 |
cofactor binding |
